Deep mutational scanning of tufted duck MHCII
Analysis by Dadonaite et al (2026)
See https://github.com/dms-vep/Tufted-duck-MHCII-DMS for full code.
Documentation of results rendered as of Wed Jul 22 15:02:54 2026
Barcode to codon-variant lookup table
Analysis notebooks
Data files
Count barcodes for variants
Analysis notebooks
Data files
Barcode count CSVs (click triangle to expand/collapse)
Functional effects of mutations
Final summary plots
Interactive plots of average mutation functional effects (click triangle to expand/collapse)
Interactive plots of average mutation functional effects from single-mutant variants only (click triangle to expand/collapse)
Analysis notebooks
- Analysis of functional scores
Notebooks with per-selection global epistasis fitting (click triangle to expand/collapse)
Notebooks averaging mutation functional effects (click triangle to expand/collapse)
Data files
Per-variant functional score CSVs (click triangle to expand/collapse)
Per-selection mutation functional effect CSVs (click triangle to expand/collapse)
Average mutation functional effects (CSV files) (click triangle to expand/collapse)
Average mutation functional effects from single-mutant variants only (CSV files) (click triangle to expand/collapse)
Average mutation latent-phenotype effects (CSV files) (click triangle to expand/collapse)
HA binding
Final summary plots
HA binding mutation effect plots (click triangle to expand/collapse)
Analysis notebooks
Fits of polyclonal models to individual HA binding selections (click triangle to expand/collapse)
Average selections for HA binding (click triangle to expand/collapse)
Data files
Probability (fraction) escape for each variant in each HA binding selection (CSVs) (click triangle to expand/collapse)
HA binding CSVs (click triangle to expand/collapse)
Integrated summary plots
entry all cells
HA binding
Additional plots
Row-wrapped heatmaps
Heatmap HTMLs